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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK3
All Species:
25.15
Human Site:
S543
Identified Species:
50.3
UniProt:
P27448
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27448
NP_001122390.1
776
87005
S543
R
T
T
A
D
R
H
S
V
I
Q
N
G
K
E
Chimpanzee
Pan troglodytes
XP_510184
737
82858
S504
R
T
T
A
D
R
H
S
V
I
Q
N
G
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868647
777
86967
S544
R
T
T
A
D
R
H
S
V
I
Q
N
G
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q03141
753
84371
S520
R
C
A
A
D
R
H
S
V
I
Q
N
G
K
E
Rat
Rattus norvegicus
Q8VHF0
797
88733
S520
R
C
A
A
D
R
H
S
V
I
Q
N
G
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
S512
R
T
T
A
D
R
H
S
V
I
Q
N
G
K
E
Chicken
Gallus gallus
Q9IA88
798
88848
V554
S
D
A
P
V
L
Q
V
Q
G
C
M
G
G
A
Frog
Xenopus laevis
NP_001084256
725
81522
S516
R
A
P
T
D
R
H
S
V
I
Q
N
G
K
E
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P755
Y
Q
S
P
S
D
S
P
P
P
T
S
L
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
N959
I
P
T
S
T
A
V
N
V
T
S
T
G
M
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
G328
L
Q
E
V
I
N
M
G
F
D
R
N
H
L
I
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
H424
F
Q
Q
Q
S
K
S
H
Q
K
S
Q
V
D
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
N.A.
96.4
N.A.
94
89.9
N.A.
90.5
31.4
85.6
26.5
N.A.
N.A.
N.A.
39.8
N.A.
Protein Similarity:
100
94.7
N.A.
97.4
N.A.
95
91.2
N.A.
92.9
50.7
89.5
42.6
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
100
6.6
80
0
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
100
6.6
80
13.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
50
0
9
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
17
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
0
59
9
0
0
0
9
0
0
0
9
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
59
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
0
0
75
9
0
% G
% His:
0
0
0
0
0
0
59
9
0
0
0
0
9
0
9
% H
% Ile:
9
0
0
0
9
0
0
0
0
59
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
9
0
0
0
9
0
0
0
59
0
% K
% Leu:
9
0
0
0
0
9
0
0
0
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
9
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
0
67
0
0
0
% N
% Pro:
0
9
9
17
0
0
0
9
9
9
0
0
0
9
9
% P
% Gln:
0
25
9
9
0
0
9
0
17
0
59
9
0
0
0
% Q
% Arg:
59
0
0
0
0
59
0
0
0
0
9
0
0
0
9
% R
% Ser:
9
0
9
9
17
0
17
59
0
0
17
9
0
0
0
% S
% Thr:
0
34
42
9
9
0
0
0
0
9
9
9
0
0
0
% T
% Val:
0
0
0
9
9
0
9
9
67
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _